“More studies are needed to determine the best practice guidelines for CO poisoning. However, the best evidence supports the use of HBO2 in acute CO poisoning, particularly Weaver’s well done 2002 study….It is better to err on the side of treating with HBO2 because the benefits of treating outweigh the risks.”
Hyperbaric Treatment of Carbon Monoxide Toxicity – StatPearls – NCBI Bookshelf (nih.gov)